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Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence
Glioma is a common brain malignancy for which new drug development is urgently needed because of radiotherapy and drug resistance. Recent studies have demonstrated that artemisinin (ARS) compounds can display antiglioma activity, but the mechanisms are poorly understood. Using cell lines and mouse m...
Autores principales: | Wei, Shupei, Liu, Lili, Chen, Zhiyu, Yin, Wenli, Liu, Yingzi, Ouyang, Qianying, Zeng, Feiyue, Nie, Yingjie, Chen, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933330/ https://www.ncbi.nlm.nih.gov/pubmed/31746143 http://dx.doi.org/10.1111/jcmm.14717 |
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