Toll‐like receptor 4 regulates spontaneous intestinal tumorigenesis by up‐regulating IL‐6 and GM‐CSF

Inflammation is as an important component of intestinal tumorigenesis. The activation of Toll‐like receptor 4 (TLR4) signalling promotes inflammation in colitis of mice, but the role of TLR4 in intestinal tumorigenesis is not yet clear. About 80%–90% of colorectal tumours contain inactivating mutati...

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Detalles Bibliográficos
Autores principales: Shi, Yun‐Jie, Zhao, Quan‐Quan, Liu, Xiao‐Shuang, Dong, Su‐He, E, Ji‐Fu, Li, Xu, Liu, Cong, Wang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933338/
https://www.ncbi.nlm.nih.gov/pubmed/31650683
http://dx.doi.org/10.1111/jcmm.14742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933338/
https://www.ncbi.nlm.nih.gov/pubmed/31650683
http://dx.doi.org/10.1111/jcmm.14742

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