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Chelerythrine induces apoptosis via ROS‐mediated endoplasmic reticulum stress and STAT3 pathways in human renal cell carcinoma

Renal cell carcinoma (RCC) is a heterogeneous histological disease and it is one of the most common kidney cancer. The treatment of RCC has been improved for the past few years, but its mortality still remains high. Chelerythrine (CHE) is a natural benzo[c]phenanthridine alkaloid and a widely used b...

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Detalles Bibliográficos
Autores principales: He, Hongchao, Zhuo, Ran, Dai, Jun, Wang, Xiaojing, Huang, Xin, Wang, Haofei, Xu, Danfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933352/
https://www.ncbi.nlm.nih.gov/pubmed/31568643
http://dx.doi.org/10.1111/jcmm.14295