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Inhibition of microRNA‐222 up‐regulates TIMP3 to promotes osteogenic differentiation of MSCs from fracture rats with type 2 diabetes mellitus

Type 2 diabetes mellitus (T2DM) is the most common diabetes and has numerous complications. Recent studies demonstrated that T2DM compromises bone fracture healing in which miR‐222 might be involved. Furthermore, tissue inhibitor of metalloproteinase 3 (TIMP‐3) that is the target of miR‐222 accelera...

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Detalles Bibliográficos
Autores principales: Jiang, Chenyi, Xia, Wenyang, Wu, Tianyi, Pan, Chenhao, Shan, Haojie, Wang, Feng, Zhou, Zubin, Yu, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933364/
https://www.ncbi.nlm.nih.gov/pubmed/31691506
http://dx.doi.org/10.1111/jcmm.14777