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α‐Mangostin suppresses the de novo lipogenesis and enhances the chemotherapeutic response to gemcitabine in gallbladder carcinoma cells via targeting the AMPK/SREBP1 cascades

High rates of de novo lipid synthesis have been discovered in certain kinds of tumours, including gallbladder cancer (GBC). Unlike several other tumours, GBC is highly insensitive to standard adjuvant therapy, which makes its treatment even more challenging. Although several potential targets and si...

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Detalles Bibliográficos
Autores principales: Shi, Yu, Fan, Yangwei, Hu, Yuan, Jing, Jiayu, Wang, Chuying, Wu, Yinying, Geng, Qianqian, Dong, Xuyuan, Li, Enxiao, Dong, Danfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933365/
https://www.ncbi.nlm.nih.gov/pubmed/31762191
http://dx.doi.org/10.1111/jcmm.14785