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Macrophage autophagy regulates mitochondria‐mediated apoptosis and inhibits necrotic core formation in vulnerable plaques

The vulnerable plaque is a key distinguishing feature of atherosclerotic lesions that can cause acute atherothrombotic vascular disease. This study was designed to explore the effect of autophagy on mitochondria‐mediated macrophage apoptosis and vulnerable plaques. Here, we generated the mouse model...

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Detalles Bibliográficos
Autores principales: Xiao, Qingqing, Che, Xinyu, Cai, Bin, Tao, Zhenyu, Zhang, Hengyuan, Shao, Qin, Pu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933382/
https://www.ncbi.nlm.nih.gov/pubmed/31660692
http://dx.doi.org/10.1111/jcmm.14715