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Genistein‐3′‐sodium sulphonate protects against lipopolysaccharide‐induced lung vascular endothelial cell apoptosis and acute lung injury via BCL‐2 signalling

Under septic conditions, Lipopolysaccharide (LPS)‐induced apoptosis of lung vascular endothelial cells (ECs) triggers and aggravates acute lung injury (ALI), which so far has no effective therapeutic options. Genistein‐3′‐sodium sulphonate (GSS) is a derivative of native soy isoflavone, which has ne...

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Detalles Bibliográficos
Autores principales: Yi, Lei, Chang, Mengling, Zhao, Quanming, Zhou, Zengding, Huang, Xiaoqin, Guo, Feng, Huan, Jingning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933390/
https://www.ncbi.nlm.nih.gov/pubmed/31756053
http://dx.doi.org/10.1111/jcmm.14815