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Glycyrrhizin mitigates radiation‐induced acute lung injury by inhibiting the HMGB1/TLR4 signalling pathway

Radiation‐induced lung injury (RILI) is the major complication of thoracic radiation therapy, and no effective treatment is available. This study explored the role of high‐mobility group box 1 (HMGB1) in acute RILI and the therapeutic effect of glycyrrhizin, an inhibitor of HMGB1, on RILI. C57BL/6 m...

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Detalles Bibliográficos
Autores principales: Zheng, Lei, Zhu, Qian, Xu, Cheng, Li, Min, Li, Huan, Yi, Pei‐Qiang, Xu, Fei‐Fei, Cao, Lu, Chen, Jia‐Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933400/
https://www.ncbi.nlm.nih.gov/pubmed/31657123
http://dx.doi.org/10.1111/jcmm.14703