Medial calcification in the arterial wall of smooth muscle cell‐specific Smpd1 transgenic mice: A ceramide‐mediated vasculopathy

Arterial medial calcification (AMC) is associated with crystallization of hydroxyapatite in the extracellular matrix and arterial smooth muscle cells (SMCs) leading to reduced arterial compliance. The study was performed to test whether lysosomal acid sphingomyelinase (murine gene code: Smpd1)‐deriv...

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Detalles Bibliográficos
Autores principales: Bhat, Owais M., Yuan, Xinxu, Cain, Chad, Salloum, Fadi N., Li, Pin‐Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933411/
https://www.ncbi.nlm.nih.gov/pubmed/31743567
http://dx.doi.org/10.1111/jcmm.14761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933411/
https://www.ncbi.nlm.nih.gov/pubmed/31743567
http://dx.doi.org/10.1111/jcmm.14761

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