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Medial calcification in the arterial wall of smooth muscle cell‐specific Smpd1 transgenic mice: A ceramide‐mediated vasculopathy
Arterial medial calcification (AMC) is associated with crystallization of hydroxyapatite in the extracellular matrix and arterial smooth muscle cells (SMCs) leading to reduced arterial compliance. The study was performed to test whether lysosomal acid sphingomyelinase (murine gene code: Smpd1)‐deriv...
Autores principales: | Bhat, Owais M., Yuan, Xinxu, Cain, Chad, Salloum, Fadi N., Li, Pin‐Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933411/ https://www.ncbi.nlm.nih.gov/pubmed/31743567 http://dx.doi.org/10.1111/jcmm.14761 |
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