Role of TGF-β/Smad Pathway in the Transcription of Pancreas-Specific Genes During Beta Cell Differentiation

Autoimmune destruction of pancreatic beta cells causes absolute insulin deficiency and results in type 1 diabetes mellitus (T1DM). The substitution of healthy pancreatic beta cells for damaged cells would be the ideal treatment for T1DM; thus, the generation of pancreatic beta cells from adult stem...

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Detalles Bibliográficos
Autores principales: Gao, Yuhua, Zhang, Ranxi, Dai, Shanshan, Zhang, Xue, Li, Xiangchen, Bai, Chunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933421/
https://www.ncbi.nlm.nih.gov/pubmed/31921861
http://dx.doi.org/10.3389/fcell.2019.00351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933421/
https://www.ncbi.nlm.nih.gov/pubmed/31921861
http://dx.doi.org/10.3389/fcell.2019.00351

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