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SampPick: Selection of a Cohort of Subjects Matching a Population HLA Distribution
Immune responses to therapeutic proteins and peptides can adversely affect their safety and efficacy; consequently, immunogenicity risk-assessments are part of the development, licensure and clinical use of these products. In most cases the development of anti-drug antibodies is mediated by T cells...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933600/ https://www.ncbi.nlm.nih.gov/pubmed/31921155 http://dx.doi.org/10.3389/fimmu.2019.02894 |