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SampPick: Selection of a Cohort of Subjects Matching a Population HLA Distribution

Immune responses to therapeutic proteins and peptides can adversely affect their safety and efficacy; consequently, immunogenicity risk-assessments are part of the development, licensure and clinical use of these products. In most cases the development of anti-drug antibodies is mediated by T cells...

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Detalles Bibliográficos
Autores principales:	McGill, Joseph R., Yogurtcu, Osman N., Verthelyi, Daniela, Yang, Hong, Sauna, Zuben E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933600/ https://www.ncbi.nlm.nih.gov/pubmed/31921155 http://dx.doi.org/10.3389/fimmu.2019.02894

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