Molecular Mechanism of the Antiproliferative Activity of Short Immunostimulating dsRNA

Small double-stranded RNAs with certain sequence motifs are able to interact with pattern-recognition receptors and activate the innate immune system. Recently, we identified a set of short double-stranded 19-bp RNA molecules with 3-nucleotide 3′-overhangs that exhibited pronounced antiproliferative...

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Detalles Bibliográficos
Autores principales: Zharkov, Mikhail I., Zenkova, Marina A., Vlassov, Valentin V., Chernolovskaya, Elena L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933605/
https://www.ncbi.nlm.nih.gov/pubmed/31921696
http://dx.doi.org/10.3389/fonc.2019.01454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933605/
https://www.ncbi.nlm.nih.gov/pubmed/31921696
http://dx.doi.org/10.3389/fonc.2019.01454

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