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Cognitively normal women with Alzheimer’s disease proteinopathy show relative preservation of memory but not of hippocampal volume

BACKGROUND: We examined interactive effects of sex, diagnosis, and cerebrospinal fluid (CSF) amyloid beta/phosphorylated tau ratio (Aβ/P-tau) on verbal memory and hippocampal volumes. METHODS: We assessed 682 participants (350 women) from BioFINDER (250 cognitively normal [CN]; and 432 symptomatic:...

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Detalles Bibliográficos
Autores principales: Caldwell, Jessica Z. K., Cummings, Jeffrey L., Banks, Sarah J., Palmqvist, Sebastian, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933621/
https://www.ncbi.nlm.nih.gov/pubmed/31878968
http://dx.doi.org/10.1186/s13195-019-0565-1