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A computational method to predict topologically associating domain boundaries combining histone Marks and sequence information

BACKGROUND: The three-dimensional (3D) structure of chromatins plays significant roles during cell differentiation and development. Hi-C and other 3C-based technologies allow us to look deep into the chromatin architectures. Many studies have suggested that topologically associating domains (TAD), a...

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Detalles Bibliográficos
Autores principales: Gan, Wei, Luo, Juan, Li, Yi Zhou, Guo, Jia Li, Zhu, Min, Li, Meng Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933632/
https://www.ncbi.nlm.nih.gov/pubmed/31881832
http://dx.doi.org/10.1186/s12864-019-6303-z