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Predicting the serum digoxin concentrations of infants in the neonatal intensive care unit through an artificial neural network

BACKGROUND: Given its narrow therapeutic range, digoxin’s pharmacokinetic parameters in infants are difficult to predict due to variation in birth weight and gestational age, especially for critically ill newborns. There is limited evidence to support the safety and dosage requirements of digoxin, l...

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Detalles Bibliográficos
Autores principales: Yao, Shu-Hui, Tsai, Hsiang-Te, Lin, Wen-Lin, Chen, Yu-Chieh, Chou, Chiahung, Lin, Hsiang-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933639/
https://www.ncbi.nlm.nih.gov/pubmed/31881933
http://dx.doi.org/10.1186/s12887-019-1895-7