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Predicting the serum digoxin concentrations of infants in the neonatal intensive care unit through an artificial neural network
BACKGROUND: Given its narrow therapeutic range, digoxin’s pharmacokinetic parameters in infants are difficult to predict due to variation in birth weight and gestational age, especially for critically ill newborns. There is limited evidence to support the safety and dosage requirements of digoxin, l...
Autores principales: | Yao, Shu-Hui, Tsai, Hsiang-Te, Lin, Wen-Lin, Chen, Yu-Chieh, Chou, Chiahung, Lin, Hsiang-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933639/ https://www.ncbi.nlm.nih.gov/pubmed/31881933 http://dx.doi.org/10.1186/s12887-019-1895-7 |
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