Focused ultrasound-induced blood-brain barrier opening improves adult hippocampal neurogenesis and cognitive function in a cholinergic degeneration dementia rat model

BACKGROUND: The persistence of adult hippocampal neurogenesis (AHN) is sharply decreased in Alzheimer’s disease (AD). The neuropathologies of AD include the presence of amyloid-β deposition in plaques, tau hyperphosphorylation in neurofibrillary tangles, and cholinergic system degeneration. The focu...

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Detalles Bibliográficos
Autores principales: Shin, Jaewoo, Kong, Chanho, Lee, Jihyeon, Choi, Bo Young, Sim, Jiyeon, Koh, Chin Su, Park, Minkyung, Na, Young Cheol, Suh, Sang Won, Chang, Won Seok, Chang, Jin Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933667/
https://www.ncbi.nlm.nih.gov/pubmed/31881998
http://dx.doi.org/10.1186/s13195-019-0569-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933667/
https://www.ncbi.nlm.nih.gov/pubmed/31881998
http://dx.doi.org/10.1186/s13195-019-0569-x

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