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Mechanistic Insights into the Effect of Ligands on Structural Stability and Selectivity of Sulfotransferase 2A1 (SULT2A1)
[Image: see text] Cytosolic sulfotransferases (SULTs) acting as phase II metabolic enzymes can be used in the sulfonation of small molecules by transferring a sulfonate group from the unique co-factor 3′-phosphoadenosine 5′-phosphosulfate (PAPS) to the substrates. In the present study, molecular dyn...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933797/ https://www.ncbi.nlm.nih.gov/pubmed/31891082 http://dx.doi.org/10.1021/acsomega.9b03136 |