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Elevated β-cell stress levels promote severe diabetes development in mice with MODY4

Maturity-onset diabetes of the young (MODY) is a group of monogenetic forms of diabetes mellitus caused by mutations in genes regulating β-cell development and function. MODY represents a heterogeneous group of non-insulin-dependent diabetes arising in childhood or adult life. Interestingly, clinica...

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Detalles Bibliográficos
Autores principales: Trojanowski, Bernadette M, Salem, Heba H, Neubauer, Heike, Simon, Eric, Wagner, Martin, Dorajoo, Rajkumar, Boehm, Bernhard O, Labriola, Leticia, Wirth, Thomas, Baumann, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933809/
https://www.ncbi.nlm.nih.gov/pubmed/31682591
http://dx.doi.org/10.1530/JOE-19-0208