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Resolving Chemical Modifications to a Single Amino Acid within a Peptide Using a Biological Nanopore

[Image: see text] While DNA sequencing is now amply available, fast, and inexpensive, protein sequencing remains a tremendous challenge. Nanopores may allow for developing a protein sequencer with single-molecule capabilities. As identification of 20 different amino acids currently presents an unsur...

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Detalles Bibliográficos
Autores principales: Restrepo-Pérez, Laura, Huang, Gang, Bohländer, Peggy R., Worp, Nathalie, Eelkema, Rienk, Maglia, Giovanni, Joo, Chirlmin, Dekker, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933820/
https://www.ncbi.nlm.nih.gov/pubmed/31536327
http://dx.doi.org/10.1021/acsnano.9b05156