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Cholesterol restricts lymphotoxin β receptor-triggered NF-κB signaling

BACKGROUND: Lymphotoxin β receptor (LTβR) plays important roles in the development of the immune system and immune response. At the cellular level, ligand-bound LTβR activates the pro-inflammatory NF-κB pathway but the detailed mechanisms regulating its signaling remain unknown. Understanding them i...

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Detalles Bibliográficos
Autores principales: Banach-Orłowska, Magdalena, Wyszyńska, Renata, Pyrzyńska, Beata, Maksymowicz, Małgorzata, Gołąb, Jakub, Miączyńska, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933913/
https://www.ncbi.nlm.nih.gov/pubmed/31878945
http://dx.doi.org/10.1186/s12964-019-0460-1