Hedgehog/GLI signaling in tumor immunity - new therapeutic opportunities and clinical implications

Uncontrolled activation of the Hedgehog/Glioma-associated oncogene (HH/GLI) pathway is a potent oncogenic driver signal promoting numerous cancer hallmarks such as proliferation, survival, angiogenesis, metastasis and metabolic rewiring. Several HH pathway inhibitors have already been approved for m...

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Detalles Bibliográficos
Autores principales: Grund-Gröschke, Sandra, Stockmaier, Georg, Aberger, Fritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933925/
https://www.ncbi.nlm.nih.gov/pubmed/31878932
http://dx.doi.org/10.1186/s12964-019-0459-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933925/
https://www.ncbi.nlm.nih.gov/pubmed/31878932
http://dx.doi.org/10.1186/s12964-019-0459-7

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