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Increased uptake of doxorubicin by cells undergoing heat stress does not explain its synergistic cytotoxicity with hyperthermia

PURPOSE: A proposed mechanism for the enhanced effectiveness of hyperthermia and doxorubicin (Dox) combinations is increased intracellular Dox concentrations resulting from heat-induced cell stress. The purpose of this study was to determine whether specific varied Dox and heat combinations produce...

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Detalles Bibliográficos
Autores principales: Sharma, Anirudh, Özayral, Sanem, Caserto, Julia S., ten Cate, Rosemarie, Anders, Nicole M., Barnett, James D., Kandala, Sri Kamal, Henderson, Elizabeth, Stewart, Jacqueline, Liapi, Eleni, Rudek, Michelle A., Franken, Nicolaas A.P., Oei, Arlene L., Korangath, Preethi, Bunz, Fred, Ivkov, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934043/
https://www.ncbi.nlm.nih.gov/pubmed/31345068
http://dx.doi.org/10.1080/02656736.2019.1631494