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Structural Insights Into TDP-43 and Effects of Post-translational Modifications

Transactive response DNA binding protein (TDP-43) is a key player in neurodegenerative diseases. In this review, we have gathered and presented structural information on the different regions of TDP-43 with high resolution structures available. A thorough understanding of TDP-43 structure, effect of...

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Detalles Bibliográficos
Autores principales: François-Moutal, Liberty, Perez-Miller, Samantha, Scott, David D., Miranda, Victor G., Mollasalehi, Niloufar, Khanna, May
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934062/
https://www.ncbi.nlm.nih.gov/pubmed/31920533
http://dx.doi.org/10.3389/fnmol.2019.00301