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Metabolism of Histone Deacetylase Proteins Opsonizes Tumor Cells to Checkpoint Inhibitory Immunotherapies

LC3-associated phagocytosis, a distinct form of autophagy, plays a key role in antigen presentation. Autophagy itself plays a central role in the regulation of cellular metabolism. Proteins that regulate autophagy include the AMPK which senses high levels of AMP, and mTOR, which integrates amino aci...

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Detalles Bibliográficos
Autores principales: Dent, Paul, Booth, Laurence, Poklepovic, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934083/
https://www.ncbi.nlm.nih.gov/pubmed/31885880
http://dx.doi.org/10.20900/immunometab20200002