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Flavivirus NS1 Triggers Tissue-Specific Vascular Endothelial Dysfunction Reflecting Disease Tropism

Flaviviruses cause systemic or neurotropic-encephalitic pathology in humans. The flavivirus nonstructural protein 1 (NS1) is a secreted glycoprotein involved in viral replication, immune evasion, and vascular leakage during dengue virus infection. However, the contribution of secreted NS1 from relat...

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Detalles Bibliográficos
Autores principales: Puerta-Guardo, Henry, Glasner, Dustin R., Espinosa, Diego A., Biering, Scott B., Patana, Mark, Ratnasiri, Kalani, Wang, Chunling, Beatty, P. Robert, Harris, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934102/
https://www.ncbi.nlm.nih.gov/pubmed/30726741
http://dx.doi.org/10.1016/j.celrep.2019.01.036