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Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs

Unconventional T cells that recognize mycobacterial antigens are of great interest as potential vaccine targets against tuberculosis (TB). This includes donor-unrestricted T cells (DURTs), such as mucosa-associated invariant T cells (MAITs), CD1-restricted T cells, and γδ T cells. We exploited the d...

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Detalles Bibliográficos
Autores principales: Ogongo, Paul, Steyn, Adrie J.C., Karim, Farina, Dullabh, Kaylesh J., Awala, Ismael, Madansein, Rajhmun, Leslie, Alasdair, Behar, Samuel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934215/
https://www.ncbi.nlm.nih.gov/pubmed/31763997
http://dx.doi.org/10.1172/JCI130711