Nested PCR and the TaqMan SNP Genotyping Assay enhanced the sensitivity of drug resistance testing of Mycobacterium leprae using clinical specimens of leprosy patients

BACKGROUND: Although leprosy is efficiently treated by multidrug therapy, resistance to first-line (dapsone, rifampin) and second-line (fluoroquinolones) drugs has been described worldwide. However, the characteristics of drug resistance in Southwest China remain unknown. Furthermore, the sensitivit...

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Detalles Bibliográficos
Autores principales: Chen, Xiaohua, He, Jun, Liu, Jian, You, Yuangang, Yuan, Lianchao, Wen, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934270/
https://www.ncbi.nlm.nih.gov/pubmed/31881061
http://dx.doi.org/10.1371/journal.pntd.0007946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934270/
https://www.ncbi.nlm.nih.gov/pubmed/31881061
http://dx.doi.org/10.1371/journal.pntd.0007946

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