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NF-κB-mediated regulation of rat CYP2E1 by two independent signaling pathways

Cytochrome P450 2E1 (CYP2E1) plays an important role in both alcohol-induced and immune-mediated liver injury. However, the mechanism underlying CYP2E1 transcriptional regulation has not been clarified. This study focused on the NF-κB-mediated transcriptional regulation of rat CYP2E1 by two independ...

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Detalles Bibliográficos
Autores principales: Lin, Qin, Kang, Xiaolin, Li, Xuefeng, Wang, Tao, Liu, Fengting, Jia, Jinxue, Jin, Ziqi, Xue, Yongzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934272/
https://www.ncbi.nlm.nih.gov/pubmed/31881060
http://dx.doi.org/10.1371/journal.pone.0225531