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A kinase-dependent checkpoint prevents escape of immature ribosomes into the translating pool

Premature release of nascent ribosomes into the translating pool must be prevented because these do not support viability and may be prone to mistakes. Here, we show that the kinase Rio1, the nuclease Nob1, and its binding partner Pno1 cooperate to establish a checkpoint that prevents the escape of...

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Detalles Bibliográficos
Autores principales: Parker, Melissa D., Collins, Jason C., Korona, Boguslawa, Ghalei, Homa, Karbstein, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934326/
https://www.ncbi.nlm.nih.gov/pubmed/31834877
http://dx.doi.org/10.1371/journal.pbio.3000329