Cargando…

Molecular structures of the human Slo1 K(+) channel in complex with β4

Slo1 is a Ca(2+)- and voltage-activated K(+) channel that underlies skeletal and smooth muscle contraction, audition, hormone secretion and neurotransmitter release. In mammals, Slo1 is regulated by auxiliary proteins that confer tissue-specific gating and pharmacological properties. This study pres...

Descripción completa

Detalles Bibliográficos
Autores principales: Tao, Xiao, MacKinnon, Roderick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934384/
https://www.ncbi.nlm.nih.gov/pubmed/31815672
http://dx.doi.org/10.7554/eLife.51409