Up-regulated fibronectin in 3D culture facilitates spreading of triple negative breast cancer cells on 2D through integrin β-5 and Src

Using MDA-MB-231 cells as a model of triple negative breast cancer (TNBC) and its metastatic sub-cell lines that preferentially metastasize to lung, bone or brain, we found that the mRNA and protein levels of fibronectin (FN) are increased in MDA-MB-231 cells and its lung metastatic derivative, when...

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Detalles Bibliográficos
Autores principales: Park, Hwa -Jeong, Helfman, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934487/
https://www.ncbi.nlm.nih.gov/pubmed/31882647
http://dx.doi.org/10.1038/s41598-019-56276-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934487/
https://www.ncbi.nlm.nih.gov/pubmed/31882647
http://dx.doi.org/10.1038/s41598-019-56276-3

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