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Restoring colistin sensitivity in colistin-resistant E. coli: Combinatorial use of MarR inhibitor with efflux pump inhibitor

Antibiotics like colistin are the last resort to deal with infections by carbapenem-resistant Enterobacteriaceae (CREB). Resistance to colistin severely restricts therapeutic options. To tackle this dire situation, urgent measures to restore colistin sensitivity are needed. In this study, whole-geno...

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Detalles Bibliográficos
Autores principales: Sundaramoorthy, Niranjana Sri, Suresh, Pavithira, Selva Ganesan, Subramaniapillai, GaneshPrasad, ArunKumar, Nagarajan, Saisubramanian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934491/
https://www.ncbi.nlm.nih.gov/pubmed/31882661
http://dx.doi.org/10.1038/s41598-019-56325-x