Neferine induces autophagy-dependent cell death in apoptosis-resistant cancers via ryanodine receptor and Ca(2+)-dependent mechanism

Resistance of cancer cells to chemotherapy is a significant clinical concern and mechanisms regulating cell death in cancer therapy, including apoptosis, autophagy or necrosis, have been extensively investigated over the last decade. Accordingly, the identification of medicinal compounds against che...

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Detalles Bibliográficos
Autores principales: Law, Betty Yuen Kwan, Michelangeli, Francesco, Qu, Yuan Qing, Xu, Su-Wei, Han, Yu, Mok, Simon Wing Fai, Dias, Ivo Ricardo de Seabra Rodrigues, Javed, Masood-ul-Hassan, Chan, Wai-Kit, Xue, Wei-Wei, Yao, Xiao-Jun, Zeng, Wu, Zhang, Hui, Wang, Jing-Rong, Liu, Liang, Wong, Vincent Kam Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934498/
https://www.ncbi.nlm.nih.gov/pubmed/31882989
http://dx.doi.org/10.1038/s41598-019-56675-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934498/
https://www.ncbi.nlm.nih.gov/pubmed/31882989
http://dx.doi.org/10.1038/s41598-019-56675-6

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