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Neferine induces autophagy-dependent cell death in apoptosis-resistant cancers via ryanodine receptor and Ca(2+)-dependent mechanism
Resistance of cancer cells to chemotherapy is a significant clinical concern and mechanisms regulating cell death in cancer therapy, including apoptosis, autophagy or necrosis, have been extensively investigated over the last decade. Accordingly, the identification of medicinal compounds against che...
Autores principales: | Law, Betty Yuen Kwan, Michelangeli, Francesco, Qu, Yuan Qing, Xu, Su-Wei, Han, Yu, Mok, Simon Wing Fai, Dias, Ivo Ricardo de Seabra Rodrigues, Javed, Masood-ul-Hassan, Chan, Wai-Kit, Xue, Wei-Wei, Yao, Xiao-Jun, Zeng, Wu, Zhang, Hui, Wang, Jing-Rong, Liu, Liang, Wong, Vincent Kam Wai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934498/ https://www.ncbi.nlm.nih.gov/pubmed/31882989 http://dx.doi.org/10.1038/s41598-019-56675-6 |
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