Human β-defensin-3 reduces excessive autophagy in intestinal epithelial cells and in experimental necrotizing enterocolitis

Necrotizing enterocolitis (NEC) is a leading cause of mortality in preterm newborns. Intestinal barrier dysfunction is one key event in NEC pathogenesis. Human β-defensin-3 (hBD3), one member of cationic host defence peptides, was reported to reduce the development of necrotizing enterocolitis in a...

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Detalles Bibliográficos
Autores principales: Chen, Liping, Lv, Zhibao, Gao, Zhimei, Ge, Guijie, Wang, Xueli, Zhou, Junmei, Sheng, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934505/
https://www.ncbi.nlm.nih.gov/pubmed/31882811
http://dx.doi.org/10.1038/s41598-019-56535-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934505/
https://www.ncbi.nlm.nih.gov/pubmed/31882811
http://dx.doi.org/10.1038/s41598-019-56535-3

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