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An optimized, robust and reproducible protocol to generate well-differentiated primary nasal epithelial models from extremely premature infants
Extremely premature infants are prone to severe respiratory infections, and the mechanisms underlying this exceptional susceptibility are largely unknown. Nasal epithelial cells (NEC) represent the first-line of defense and adult-derived ALI cell culture models show promising results in mimicking in...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934534/ https://www.ncbi.nlm.nih.gov/pubmed/31882915 http://dx.doi.org/10.1038/s41598-019-56737-9 |