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K(Ca)3.1 channel blockade attenuates microvascular remodelling in a large animal model of bleomycin-induced pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with limited therapeutic options and poor prognosis. IPF has been associated with aberrant vascular remodelling, however the role of vascular remodelling in pulmonary fibrosis is poorly understood. Here, we used a novel segmen...
Autores principales: | Derseh, Habtamu B., Dewage, Sasika N. Vithana, Perera, Kopiyawaththage U. E., Pagel, Charles N., Koumoundouros, Emmanuel, Organ, Louise, Snibson, Ken J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934539/ https://www.ncbi.nlm.nih.gov/pubmed/31882807 http://dx.doi.org/10.1038/s41598-019-56412-z |
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