P2X7 Receptor Stimulation Is Not Required for Oxalate Crystal-Induced Kidney Injury

Oxalate crystal-induced renal inflammation is associated with progressive kidney failure due to activation of the NLRP3/CASP-1 inflammasome. It has been suggested previously that purinergic P2X7 receptor signaling is critical for crystal-induced inflammasome activation and renal injury. Therefore, w...

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Detalles Bibliográficos
Autores principales: Luz, Hannah L., Reichel, Martin, Unwin, Robert J., Mutig, Kerim, Najenson, Ana C., Tonner, Louise M., Eckardt, Kai-Uwe, Tam, Frederick W. K., Knauf, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934555/
https://www.ncbi.nlm.nih.gov/pubmed/31882798
http://dx.doi.org/10.1038/s41598-019-56560-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934555/
https://www.ncbi.nlm.nih.gov/pubmed/31882798
http://dx.doi.org/10.1038/s41598-019-56560-2

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