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P2X7 Receptor Stimulation Is Not Required for Oxalate Crystal-Induced Kidney Injury
Oxalate crystal-induced renal inflammation is associated with progressive kidney failure due to activation of the NLRP3/CASP-1 inflammasome. It has been suggested previously that purinergic P2X7 receptor signaling is critical for crystal-induced inflammasome activation and renal injury. Therefore, w...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934555/ https://www.ncbi.nlm.nih.gov/pubmed/31882798 http://dx.doi.org/10.1038/s41598-019-56560-2 |