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Conformational and functional characterization of artificially conjugated non-canonical ubiquitin dimers

Ubiquitylation is an eminent posttranslational modification referring to the covalent attachment of single ubiquitin molecules or polyubiquitin chains to a target protein dictating the fate of such labeled polypeptide chains. Here, we have biochemically produced artificially Lys11-, and Lys27-, and...

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Detalles Bibliográficos
Autores principales: Schneider, Tobias, Berg, Andrej, Ulusoy, Zeynel, Gamerdinger, Martin, Peter, Christine, Kovermann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934565/
https://www.ncbi.nlm.nih.gov/pubmed/31882959
http://dx.doi.org/10.1038/s41598-019-56458-z