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Experimental arthritis and Porphyromonas gingivalis administration synergistically decrease bone regeneration in femoral cortical defects

Porphyromonas gingivalis infection can lead to periodontitis and dysbiosis, which are known risk factors for rheumatoid arthritis (RA). We investigated whether P. gingivalis administration affected bone regeneration in mice with or without arthritis. We administered P. gingivalis to male DBA/1 J mic...

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Detalles Bibliográficos
Autores principales: Okumura, Go, Kondo, Naoki, Sato, Keisuke, Yamazaki, Kazuhisa, Ohshima, Hayato, Kawashima, Hiroyuki, Ogose, Akira, Endo, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934576/
https://www.ncbi.nlm.nih.gov/pubmed/31882624
http://dx.doi.org/10.1038/s41598-019-56265-6