C. elegans expressing D76N β(2)-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis

The availability of a genetic model organism with which to study key molecular events underlying amyloidogenesis is crucial for elucidating the mechanism of the disease and the exploration of new therapeutic avenues. The natural human variant of β(2)-microglobulin (D76N β(2)-m) is associated with a...

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Detalles Bibliográficos
Autores principales: Faravelli, Giulia, Raimondi, Sara, Marchese, Loredana, Partridge, Frederick A., Soria, Cristina, Mangione, P. Patrizia, Canetti, Diana, Perni, Michele, Aprile, Francesco A., Zorzoli, Irene, Di Schiavi, Elia, Lomas, David A., Bellotti, Vittorio, Sattelle, David B., Giorgetti, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934621/
https://www.ncbi.nlm.nih.gov/pubmed/31882874
http://dx.doi.org/10.1038/s41598-019-56498-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934621/
https://www.ncbi.nlm.nih.gov/pubmed/31882874
http://dx.doi.org/10.1038/s41598-019-56498-5

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