Inducing Tumor Suppressive Microenvironments through Genome Edited CD47(−/−) Syngeneic Cell Vaccination

Tumors can escape from the immune system by overexpressing CD47 and other checkpoint blockades. CD47 is expressed ubiquitously by all cells in the body, posing an obstacle for CD47 blocking treatments due to their systemic toxicity. We performed a study to determine how the tumor microenvironment ch...

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Detalles Bibliográficos
Autores principales: Jayaraman Rukmini, Subhadra, Bi, Huanjing, Sen, Puloma, Everhart, Benjamin, Jin, Sha, Ye, Kaiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934648/
https://www.ncbi.nlm.nih.gov/pubmed/31882679
http://dx.doi.org/10.1038/s41598-019-56370-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934648/
https://www.ncbi.nlm.nih.gov/pubmed/31882679
http://dx.doi.org/10.1038/s41598-019-56370-6

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