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Inducing Tumor Suppressive Microenvironments through Genome Edited CD47(−/−) Syngeneic Cell Vaccination
Tumors can escape from the immune system by overexpressing CD47 and other checkpoint blockades. CD47 is expressed ubiquitously by all cells in the body, posing an obstacle for CD47 blocking treatments due to their systemic toxicity. We performed a study to determine how the tumor microenvironment ch...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934648/ https://www.ncbi.nlm.nih.gov/pubmed/31882679 http://dx.doi.org/10.1038/s41598-019-56370-6 |