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Effective lung-targeted RNAi in mice with peptide-based delivery of nucleic acid

We have previously developed efficient peptide-based nucleic acid delivery vectors PF14 and NF55, where we have shown that these vectors preferentially transfect lung tissue upon systemic administration with the nucleic acid. In the current work, we have explored the utilization and potential of the...

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Detalles Bibliográficos
Autores principales: Kurrikoff, Kaido, Freimann, Krista, Veiman, Kadi-Liis, Peets, Elin Madli, Piirsoo, Andres, Langel, Ülo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934651/
https://www.ncbi.nlm.nih.gov/pubmed/31882941
http://dx.doi.org/10.1038/s41598-019-56455-2