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Effective lung-targeted RNAi in mice with peptide-based delivery of nucleic acid
We have previously developed efficient peptide-based nucleic acid delivery vectors PF14 and NF55, where we have shown that these vectors preferentially transfect lung tissue upon systemic administration with the nucleic acid. In the current work, we have explored the utilization and potential of the...
Autores principales: | Kurrikoff, Kaido, Freimann, Krista, Veiman, Kadi-Liis, Peets, Elin Madli, Piirsoo, Andres, Langel, Ülo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934651/ https://www.ncbi.nlm.nih.gov/pubmed/31882941 http://dx.doi.org/10.1038/s41598-019-56455-2 |
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