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Deep sequencing and automated histochemistry of human tissue slice cultures improve their usability as preclinical model for cancer research
Cancer research requires models closely resembling the tumor in the patient. Human tissue cultures can overcome interspecies limitations of animal models or the loss of tissue architecture in in vitro models. However, analysis of tissue slices is often limited to histology. Here, we demonstrate that...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934722/ https://www.ncbi.nlm.nih.gov/pubmed/31882946 http://dx.doi.org/10.1038/s41598-019-56509-5 |