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Deep sequencing and automated histochemistry of human tissue slice cultures improve their usability as preclinical model for cancer research

Cancer research requires models closely resembling the tumor in the patient. Human tissue cultures can overcome interspecies limitations of animal models or the loss of tissue architecture in in vitro models. However, analysis of tissue slices is often limited to histology. Here, we demonstrate that...

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Detalles Bibliográficos
Autores principales: Haehnel, Susann, Reiche, Kristin, Loeffler, Dennis, Horn, Andreas, Blumert, Conny, Puppel, Sven-Holger, Kaiser, Nicole, Rapp, Felicitas, Rade, Michael, Horn, Friedemann, Meixensberger, Juergen, Bechmann, Ingo, Gaunitz, Frank, Winter, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934722/
https://www.ncbi.nlm.nih.gov/pubmed/31882946
http://dx.doi.org/10.1038/s41598-019-56509-5